Botanical Index No. 263

Cinchona

Safety & Contraindications

Commission E reports contraindications; pregnancy and hypersensitivity; adverse effects: allergic reactions, rarely thrombocytopenia; and interaction: potentiation of coumarin derivatives. Other sources report contraindication for GI-ulcer, adverse effects for allergic skin reactions and fever. Overdosing or prolonged use may produce toxic effects. 8–20 g quinine may be fatal in humans.

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