Botanical Index No. 574

Jiaogulan

gynostemma pentaphyllum

Medicinal Actions

Antiaggregant, Antiatherosclerotic, Anticancer, Antiedemic, Antifibrotic, Antiinflammatory, Antiischemic, Antioxidant, Antiradicular, Antisenility, Antistroke, Antithrombic, Apoptotic, Cardioprotective, Cardiotonic, Chemopreventive, Hematopoetic, Hepatoprotective, Hypertensive, Hypocholesterolemic, Hypolipidemic, Hypotensive, Immunostimulant, Leukocytogenic, NO-genic, Radioprotective, SOD-genic, High Triglyceride

Primary Conditions Treated

Adaptogen Immunomodulator Altitude Sickness Atherosclerosis Bronchosis Cancer esophagus Cardiopathy Diabetes Dysplasia Esophagosis Fibrosis Flourosis Hepatosis High Blood Pressure High Cholesterol Hyperlipidemia Hyperproteinemia Immunodepression Impotence Inflammation Insomnia Ischemia Leukopenia Leukoplasia Low Blood Pressure Obesity PMS Senility Stress Stroke Swelling Thrombosis

General Dosage

In an interesting departure, Blumert and Liu give dosage recommendations, indication by indication, based on StX 20 mg tablets; in general, the preventive dose is 20 mg 2–3 ×/day, while the therapeutic dose is 60 mg 2–3 ×/day; other experimental data reported 5–10 mg/kg ivn dog; 20 mg gypenosides orl man 3 ×/day/1 mo; 20 mg gypenosides orl man 2 ×/day/3 mos; water extract with 30 mg gypenosides; and 1 ml/kg body weight. Standardization may soon produce products with 85% gypenosides.

Safety & Contraindications

I don’t find this in any of my books. Hence I have no negative information. Gypenosides LD50 = >100 × therapeutic dose.

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