Botanical Index No. 531

Hydrangea

hydrangea arborescens

Safety & Contraindications

Class 2d. Not for prolonged use. Do not exceed recommended dose. Cyanogenic properties. “Hazards and/or side effects not known for proper therapeutic dosages”. CAN cautions regarding GI irritation and dermatosis. Overdoses may cause tightness in chest and vertigo. Hydrangin may cause gastrosis and enterosis. And the cop-out clause. In view of the “lack of” data, use during pregnancy and lactation, and excessive use should be avoided. Extract is nontoxic in animals. Hydrangenol is allergenic. Flavonoids such as quercetin and rutin are said to be diuretic, to inhibit tumor formation, and to reduce inflammation. Synthesized hydrangeol derivatives are reportedly antiallergic, inhibiting hyaluronidase activity and histamine release.

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